By 1910 the Cambridge University physiology department had become the kernel of British physiology. Between 1909 and 1914 an astonishing number of young and talented scientists passed through the laboratory. The University College department was also a stimulating place of study under the dynamic leadership of Ernest Starling.I have argued that the reasons for this metropolitan axis within British physiology lie with the social structure of late-Victorian and Edwardian higher education. Cambridge, Oxford, and University College London were national institutions attracting (...) students from all over England and Wales. In contrast, the provincial colleges drew their clientele from relatively narrow geographic radii. Generally, also, these institutions were regarded as socially inferior to the longer-established universities.A brief survey of the biographies of some British physiologists demonstrates how physiology, as an occupation, became, over the later decades of the century, socially elite. The scientists who achieved full-time posts in the 1870s generally came from somewhat marginal backgrounds. Foster, like his mentors T. H. Huxley and William Sharpey, came from a non-conformist family. Edward Schäfer was also a dissenter and, like Foster, began his professional career as a general practitioner.Physiologists of the succeeding generation, however, came from wealthy families with established intellectual traditions. John Scott Haldane, nephew of John Burdon Sanderson, was the brother of the politician R. B. Haldane and uncle of the historian A. R. B. Haldane.71 Joseph Barcroft was one of the most affluent of all physiologists.72 His family's wealth derived from linen manufacturing. He attended the Ley's School Cambridge, where his schoolmates included Henry Dale, later Director of the National Institute for Medical Research; F. A. Bainbridge, who eventually became Professor of Physiology at St. Bartholomew's Hospital; and the Cambridge historian J. H. Clapham. A. V. Hill, Professor of Physiology at Manchester and, subsequently, London, married Margaret Keynes, sister of John Maynard Keynes and niece of Sir Walter Langdon Brown, Professor of Physic at Cambridge. Margaret Keynes's younger brother, the surgeon Sir Geoffrey Keynes, married a granddaughter of Charles Darwin; their son Richard Keynes also became a physiologist at Cambridge.These families were part of a new class emerging during the late Victorian period, descendants of the great reforming radicals of the 1830s, who had begun to achieve power through positions in the universities, the professions, and the civil service. Their social prestige rested upon their intellectual expertise. Physiology was an appealing research discipline to these groups because of its clear dissociation from industry and commerce. And because physiology's “practical” face was medicine, its acceptability was reinforced by professional ties.The nature of the Physiological Society confirms this image of physiology as an elite science. By the turn of the century the Society had taken on some of the characteristics of a dining club. The scientific meetings were generally followed by dinner: if the Society met at Oxford, they were entertained at Burdon Sanderson's college, Magdalen.73 Through a “black ball” system, unwanted candidates could be excluded. In 1912, when the question of admitting foreigners was discussed, E. H. Starling wrote to Edward Schäfer: “the Society has very much in it the nature of a club, and a certain amount of personal knowledge of the candidate is always desirable.”74.The developing institutional structure of physiology in late Victorian Britain indicates, therefore, that we must look beyond the achievements of individuals and departments to understand why physiology flourished. The discipline became part of a new social order in which the professional middle classes assumed increasing power. These groups valued intellectual skill, especially in the pure scienes, as forces both for self-advancement and for progress within society. (shrink)

Using a large sample of retail investors as well as experimental data we find that risk and ambiguity aversion are positively correlated. We provide evidence that a common link is decision mode: intuitive thinkers tolerate more risk and ambiguity than effortful reasoners. One interpretation is that intuitive thinking confers an advantage in risky or ambiguous situations. We present supporting lab and field evidence that intuitive thinkers outperform others in uncertain environments. Finally, we find that risk and ambiguity aversion vary with (...) individual characteristics and wealth. The wealthy are less risk averse but more ambiguity averse, which has implications for financial puzzles. (shrink)

F. H. George is Professor of Cybernetics at Brunel University in England. His book comprises eight chapters originally developed as lectures for a non-specialist audience. He points out the position of computer science among the sciences, explains its aims, procedures, and achievements to date, and speculates on its long-term implications for science in particular and society in general. Among the topics discussed are biological simulation and organ replacement, automated education, and the new philosophy of science. Each chapter concludes with a (...) brief summary. George's treatment of the technical details of his speciality is both illuminating and readable, thus serving as an excellent primer on one of the new technology's most important components. His wider forays into philosophy, economics, sociology, and religion are less happy, however; and unfortunately they take up a large part of the text. In general, they reveal that George identifies the methods of human advancement with the methods of the natural sciences in an equation whose rigidity would make even B. F. Skinner blush. Yet, the reader cannot claim that he was not forewarned; for in the introduction, D. J. Stewart, Chairman of the Rationalist Press Association, suggests that the current "swing of interest among young people away from the physical and biological sciences and towards the behavioural and social sciences... represents a symptom of disillusionment with science and technology and an attempted escape into irrationality."--J. M. V. (shrink)

In this, his first book, originally published in 1926, Henry Nelson Wieman sets forth a view on the relationship of religious experience and scientific method which in substance he has maintained ever since. According to Wieman, our knowledge of the concrete world consists of immediate sensuous experience as interpreted through some set of concepts. Religious experience is the richest form of immediate sensuous experience. It is our awareness of God, who is as much an object of experience as are tree (...) and hill and stone. And scientific method is the systematic procedure by which the conceptual network for interpreting immediate sensuous experience is clarified and corrected, with the experience-concept compound thus becoming "science." Religious experience, therefore, receives its most adequate interpretation in science; while science, in turn, receives its most stimulating input from religious experience. In principle, the highest of the individual sciences is theology; in fact, however, the very complexity of religious experience and the difficulty of distinguishing it clearly from other types of immediate sensuous experience have prevented more than merely minimal progress in achieving a truly scientific theology. On the whole our ideas about God are marked by confusion and controversy, therefore, despite the fact that some of these notions probably are true. Wieman’s book serves as an excellent example of the liberal thought which dominated much of theology and philosophy-of-religion during the last part of the nineteenth century and the first part of the twentieth. The religious thinker with a liberal perspective conceives his primary challenge as developing a scientifically acceptable interpretation of religious experience, taking that experience itself as being obvious and almost universally recognized. One need not be particularly well read to know that current judgments regarding the obviousness of religious experience are hardly so sanguine, however, and that the religious thinker typical of our own age therefore conceives his primary challenge quite differently.—J. M. V. (shrink)

Butchvarov is chairman of the department of philosophy at the University of Iowa. His book, a contribution to a new series, the Northwestern University Publications in Analytical Philosophy, deals with "the conceptual foundations of epistemology." It is divided into four main parts. The first undertakes an account of the general concept of knowledge. The second treats the objects of a priori knowledge; the third, the nature of primary a posteriori knowledge. The fourth part regards nondemonstrative inference and the nature of (...) derivative knowledge in general. The focus of the book is upon fundamental epistemic concepts rather than such particular issues as knowledge of the future, of bodies, of other minds, etc. Butchvarov urges that such specialized problems be treated only after the general conceptual framework has been investigated, lest one's common-sense opinions on the former unduly influence his philosophical conclusions as to the latter. For the inherent demands of the discipline itself must be respected: "In philosophy, as in any other purely theoretical discipline, it is better to be wrong as the result of inquiry and argument than to be right as the result of mere conviction." One of the author's central conclusions concerns evidential criteria. One unquestionable criterion of evidence is the impossibility of mistake, the "demonstrative" criterion. Is there, in addition, any "nondemonstrative" criterion of evidence, with the consequent possibility of nondemonstrative derivative knowledge or at least nondemonstrative rational belief? While not ruling out the possibility of such a criterion, Butchvarov judges that at least one has not yet been brought forth. Particular criteria proposed as nondemonstrative, such as inductive and behavioral, either presuppose the demonstrative criterion or else lack intelligible content. More generally, the nondemonstrative criterion either would or would not possess something in common with the demonstrative criterion, such that both could be understood as species of the same genus, "criterion of evidence." But no successful attempt has thus far been made in showing just what this shared trait might be; and the thesis that there can be multiple criteria of evidence without any generic commonality equivocates on the very notion of evidence. It follows, therefore, that knowledge and rational belief are much more restricted than one would ordinarily surmise. This book manifests both the scholar's mastery of his field and the teacher's concern for clear, well-structured presentation. It reads well, employs good examples, and includes the all-important index.--J. M. V. (shrink)

Anders Nygren is widely known among English-speaking readers for his subtle and scholarly analysis of the forms of love, Agape and Eros, first published in 1930. Important facets of his far-ranging thought, however, have remained largely inaccessible to those who do not read Swedish. The present volume is a significant step in reducing that inaccessibility. Nygren's work is treated by seventeen different contributors in essays grouped under the following headings: Philosophy of Religion, Motif Research, The Meanings of Love, Systematic Theology, (...) Ethics, and Cultural and Ecumenical Concerns. Yet the book is more than merely a Festschrift. Over ten years in preparation, it aims at criticism as well as interpretation; and it includes an introductory "intellectual autobiography" by Nygren himself, a concluding response by Nygren to each of his critics, and a complete bibliography chronicling the 372 items published by Nygren from 1918 through 1970. Nygren's investigations fall on both sides of the line between philosophy and theology. The interest which unifies these inquiries is the philosophy of religion. "It is above all in the philosophy of religion that the great decisions are finally made." Nygren's earliest work was an attempt to establish the philosophy of religion on a purely scientific basis. It was in this regard that he developed his characteristic method of "motif research." Just as the supreme theoretical, aesthetic, and ethical categories are the true, the beautiful, and the good, respectively, so the supreme religious category is the eternal. All these categories are merely formal, however, and one must turn to the particular for content. Now, content in the theoretical domain consists of factual relationships; but content in the remaining three, "atheoretical," domains consists of the values or "fundamental motifs" which have been chosen from among a limited number of basic alternatives by a given historical group. The scholar forms a hypothesis regarding the fundamental motifs of the group in question; and if this hypothesis is verified by historical research, it then serves as a principle for organizing additional data concerning the group. Thus, the philosopher-historian of religion studies groups in an effort to determine their answers to the question, "What is the eternal?" It is chiefly in this domain that Nygren has applied his method, concluding, for example, that "agape" and "eros" are the characteristic Christian and Greek answers, respectively, to the fundamental religious question. Nygren maintains that this approach provides the means for treating the religious question systematically while simultaneously respecting the vast historical diversity of specific religious content. Just as the method of motif research is central to Nygren's work, so the discussion of that method and its applications constitutes, in effect, the central matter of this book. The project is carried off well. Nygren's final commentary is especially welcome, confirming or correcting positions presented by the contributors as his, and accepting or rejecting positions advanced by the contributors as their own.--J. M. V. (shrink)

1. The Commentariolum Petitionis is not in the Codex Mediceus of Cicero's correspondence with his brother Quintus, but it appears at the end of the letters to Quintus in the other manuscripts. It starts in the normal manner of a letter and is, or purports to be, a collection of tips on canvassing set in the particular context of M. Cicero's consular candidature in 64: a composition of his brother Quintus. It is printed as no. 12 in Tyrrell and Purser's (...) collection of Cicero's Letters. (shrink)

A new approach to landscape ecology involves the application of the eco-field hypothesis and the General Theory of Resources. In this study, we describe the putative eco-field of bark beetles as a spatial configuration with a specific meaning-carrier for every organism-resource interaction. Bark beetles are insects with key roles in matter and energy cycles in coniferous forests, which cause significant changes to forestry landscapes when outbreaks occur. Bark beetles are guided towards host trees by the recognition of semiotic signals using (...) a specific eco-field. These signals mainly comprise a group of scents, which are called the odourtope. Their interactions with other organisms occur by sharing relevant information from the eco-field networks in the forest ecosystem. The eco-field networks modulate the expansion of the realized semiotic niche of the bark beetle towards the potential semiotic niche. Moreover, the niche construction process can be initiated by interchanging signals among species living in the same place, where these signals allow the exploitation of the required resources. If different organisms are interdependent on signals in eco-field networks, then this process may result in the establishment of mutualistic relationships. This is an example of how evolutionary processes are initiated by the recognition of signals in a network of eco-fields. (shrink)

Of the early Roman historians who wrote in Greek, A. Postumius Albinus was not necessarily alone in realizing that his Greek was not the best Greek; while, on the other hand, Cato and those who followed the new fashion of writing in Latin would have resented, we may assume, could they have foreknown, the statement of Q,. Catulus in Cicero's De Oratore that they had no literary or rather ‘oratorical’ merit; though Cato might have approved Catulus' caustic comment on Roman (...) historical writing, ‘Satis est non esse mendacem’. That an historian should not, consciously and deliberately, lie all second-century historians would no doubt have agreed; and they would have endorsed Polybius' condemnation of masquerading as history in a story whose falseness was self-evident, because it assumed, on the part of the young sons of senators at Rome, a gravitas such as no young boy could possibly possess. (shrink)

Social networking sites (SNS) are of increasing importance for adolescents’ social life. As adolescents are prone to display risky health behavior in the offline world, it is likely that they use their online profiles and communications to report on unhealthy behaviors, too. This may in turn enhance the perceived attractiveness of risky behavior within the adolescent cohort. Drawing on the insights of impression management theory, we argue in this article that adolescents use a variety of impression management tactics in their (...) SNS profiles and communications. Following this assumption, our empirical analysis of 5851 Facebook posts (profile texts, comments, photographs, etc.) shows that the users tend to associate risky health behaviors with positive attributes, such as accomplishment or sociability, to present themselves in an attractive way to their online peer audience. We argue that this raises two ethical issues relevant to health promotion: Adolescents’ health may be challenged by interaction on SNS, as their engagement in online impression management blanks out any health problems or critical assessments of risky health behavior. At the same time, the semi-public nature of the communication arena re-enforces the tendency to value unhealthy behavior as more attractive than in offline social interactions. (shrink)

‘Auctoritas’ was naturally one of Cicero's favourite concepts. In the ideal republic power lay with the people, auctoritas with the Senate . Alternatively, in a balanced state, potestas would lie with the magistrates, libertas with the people, but still auctoritas would be the property of the Senate, ‘in principum consitio’ [De rep. 2. 57).

During an Australian qualitative and empirical study looking at lesbian, gay, bisexual, and transgender client's experiences of counseling, and counselor's experiences of working with minority clients, a large body of unsolicited data emerged related to experiences of religious-based homophobia. Analysis of the data suggests that a lifelong process of posttraumatic recovery for many lesbian, gay, bisexual, and transgender people follows prior experiences of religious-based homophobia. This paper discusses the sociological debate related to how counselors find themselves at the crossroad between (...) a healthy lifestyle model of homosexuality based in well established contemporary professional ethics versus long standing religious-based attitudes and constraints toward homosexuality. This intersection of conflicting beliefs generates a controversial social and political environment in which counselors must make a basic decision to either support minority clients according to ethical guidelines or to side with socially conservative constructs that, rightly or wrongly, rely largely on Western religious traditions. (shrink)

Although agricultural mechanization, hybrid cultivars, the Green Revolution, and modern biotechnology have been implemented on a global scale, conventional farmers still have to face a lot of ethical debate and criticism. From a plants ethics perspective, they are challenged by organic farmers to reorganize their practices in a responsible way, and no longer consider plants as mere instruments. However, by embracing the development of precision farming, conventional crop production seems to turn in the opposite direction and tends to become large-scale (...) digitalized robot farming. By integrating many kinds of data, precision farming technologies can be conceived as creating ‘digital’ plants as next step in the instrumentalization of crop plants. In this chapter we first discuss the main approaches to plant ethics. We use the concept of “flourishing” as our starting point for addressing the moral status of plants. On this basis, we develop a framework for ‘digital’ plants and apply it to several key technologies that have influenced the development of precision farming: sensing technologies, data processing and utilization, and control technologies. Finally, we discuss the possibility to develop a responsible precision farming of crop plants, based on a plant ethics of flourishing. (shrink)

The practice of killing day-old chicks in the Dutch egg sector is a recurrent subject of societal debate. Preventing the killing of young animals and in ovo sex determination are the two main alternatives for this problem available. An online questionnaire was held to ask the opinion of the Dutch public about these alternatives. The results show that no alternative will be fully accepted, or accepted by more than half of Dutch society. However, the survey does provide an insight to (...) what people think is important for their choice: food safety and a good treatment of animals. Irrespective of the alternative chosen, these values should be safeguarded and communicated clearly. (shrink)

This paper reports a study of the roles of visuo-spatial and verbal working memory capacities in solving a planning task - the five-disc Tower of London (TOL) task. An individual differences approach was taken. Sixty adult participants were tested on 20 TOL tasks of varying difficulty. Total moves over the 20 TOL tasks was taken as a measure of performance. Participants were also assessed on measures of fluid intelligence (Raven's matrices), verbal short-term storage (Digit span), verbal working memory span (Silly (...) Sentence span), visuo-spatial short-term storage (Visual Pattern span and Corsi Block span), visuo-spatial working memory (Corsi Distance Estimation), visuo-spatial processing speed (Manikin test), and verbal speed (Rehearsal speed). Exploratory factor analysis using an oblique rotation method revealed three factors which were interpreted as (1) a visuo-spatial working memory factor, (2) an age-speed factor, and (3) a verbal working memory factor. The visuo-spatial and verbal factors were only moderately correlated. Performance on the TOL task loaded on the visuo-spatial factor but did not load on the other factors. It is concluded that the predominant goal-selection strategy adopted in solving the TOL relies on visuo-spatial working memory capacity and particularly involves the active ''inner scribe'' spatial rehearsal mechanism. These correlational analyses confirm and extend results previously obtained by use of dual task methods, (Phillips, Wynn, Gilhooly, Della Sala, & Logie, 1999). (shrink)

It is a pleasure to read Hume, and to watch him explore recalcitrant problems with agility of mind and grace of style. Ironically these twin abilities have worked against each other from the beginning, in the first place because in the matter of writing Hume was an innovator — nobody before him had so successfully albeit unwittingly adapted French syntax to the writing of English-and-Scottish - and in the second place because on the grace of his style subtleties of thought (...) flow past his readers, who then accuse him of obscurity. So abstruse were his writings to his contemporaries that he failed to achieve the literary recognition for which he craved; and even today, long after the elegance of his style has been received, it is said by Passmore that Hume in contrast to Berkeley ‘was a philosophical puppy-dog, picking up and worrying one problem after another, always leaving his teeth-marks in it, but casting it aside when it threatened to become wearisome.’ Similarly Selby-Bigge says in his introduction to the Enquiries:His pages, especially those of the Treatise, are so full of matter, he says so many things in so many different ways and different connexions, and with so much indifference to what he has said before, that it is very hard to say positively that he taught, or did not teach, this or that particular doctrine. He applies the same principles to such a great variety of subjects that it is not surprising that many verbal, and some real inconsistencies can be found in his statements. He is ambitious rather than shy of saying the same thing in different ways, and at the same time he is often slovenly and indifferent about his words and formulae. This makes it easy to find all philosophies in Hume, or, by setting up one statement against another, none at all. (shrink)

The objective of the study was to investigate the relationship between childhood IQ of parents and characteristics of their adult offspring. It was a prospective family cohort study linked to a mental ability survey of the parents and set in Renfrew and Paisley in Scotland. Participants were 1921-born men and women who took part in the Scottish Mental Survey in 1932 and the Renfrew/Paisley study in the 1970s, and whose offspring took part in the Midspan Family study in 1996. There (...) were 286 offspring from 179 families. Parental IQ was related to some, but not all characteristics of offspring. Greater parental IQ was associated with taller offspring. Parental IQ was inversely related to number of cigarettes smoked by offspring. Higher parental IQ was associated with better education, offspring social class and offspring deprivation category. There were no significant relationships between parental IQ and offspring systolic blood pressure, diastolic blood pressure, cholesterol, glucose, lung function, weight, body mass index, waist hip ratio, housing, alcohol consumption, marital status, car use and exercise. Structural equation modelling showed parental IQ associated with offspring education directly and mediated via parental social class. Offspring education was associated with offspring smoking and social class. The smoking finding may have implications for targeting of health education. (shrink)

Categories We Live By makes several claims about Judith Butler's Gender Trouble which Butler seeks to contest, while remaining in fundamental agreement with most of the conclusions in Asta Sveinsdottir's book. At issue is whether or not performativity can rightly be restricted to what is called an exercitive in J. L. Austin's sense, whether Butler is a radical constructivist or a qualified one, and whether unauthorized speech acts have a power to bring a reality into being that (...) is different from those authorized by legal regimes. Along the way, Butler suggest that establishing facts takes place within variable historical schemes and that this argument is neither a denial or facts nor of materiality. Finally, an individualist idea of freedom is subject to criticism in order to make way for an historically constrained freedom, collective in nature. (shrink)

Multiple cortical areas of the human brain motor system interact coherently in the low frequency range (< 0.1 Hz), even in the absence of explicit tasks. Following stroke, cortical interactions are functionally disturbed. How these interactions are affected and how the functional organization is regained from rehabilitative treatments as people begin to recover motor behaviors has not been systematically studied. We recorded the intrinsic functional magnetic resonance imaging (fMRI) signals from 30 participants: 17 young healthy controls and 13 aged stroke (...) survivors. Stroke participants underwent mental practice (MP) or both mental practice and physical therapy (MP + PT) within 14-51 days following stroke. We investigated the network activity of five core areas in the motor-execution network, consisting of the left primary motor area (LM1), the right primary motor area (RM1), the left pre-motor cortex (LPMC), the right pre-motor cortex (RPMC) and the supplementary motor area (SMA). We discovered that (i) the network activity dominated in the frequency range 0.06 Hz – 0.08 Hz for all the regions, and for both able-bodied and stroke participants (ii) the causal information flow between the regions: LM1 and SMA, RPMC and SMA, RPMC and LM1, SMA and RM1, SMA and LPMC, was reduced significantly for stroke survivors (iii) the flow did not increase significantly after MP alone and (iv) the flow among the regions during MP+PT increased significantly. We also found that sensation and motor scores were significantly higher and correlated with directed functional connectivity measures when the stroke-survivors underwent MP+PT but not MP alone. The findings provide evidence that a combination of mental practice and physical therapy can be an effective means of treatment for stroke survivors to recover or regain the strength of motor behaviors, and that the spectra of causal information flow can be used as a reliable biomarker for evaluating rehabilitation in stroke survivors. (shrink)

Inattentional blindness is described as the failure to perceive a supra-threshold stimulus when attention is directed away from that stimulus. Based on performance on an explicit recognition memory test and concurrent functional imaging data Rees, Russell, Frith, and Driver [Rees, G., Russell, C., Frith, C. D., & Driver, J. . Inattentional blindness versus inattentional amnesia for fixated but ignored words. Science, 286, 2504–2507] reported inattentional blindness for word stimuli that were fixated but ignored. The present study examined both explicit and (...) implicit memory for fixated but ignored words using a selective-attention task in which overlapping picture/word stimuli were presented at fixation. No explicit awareness of the unattended words was apparent on a recognition memory test. Analysis of an implicit memory task, however, indicated that unattended words were perceived at a perceptual level. Thus, the selective-attention task did not result in perfect filtering as suggested by Rees et al. While there was no evidence of conscious perception, subjects were not blind to the implicit perceptual properties of fixated but ignored words. (shrink)

I argue, contrary to wide-spread opinion, that belief-desire psychology is likely to reduce smoothly to neuroscientific theory. I therefore reject P.M. Churchland's eliminativism and Fodor's nonreductive materialism. The case for this claim consists in an example reduction of the desire construct to a suitable construct in neuroscience. A brief account of the standard view of intertheoretic reduction is provided at the outset. An analysis of the desire construct in belief-desire psychology is then undertaken. Armed with these tools, the paper moves (...) to an examination of the neural structures responsible for the production of motor behavior. This examination provides the basis for a theory of the neurophysiology of desire. A neurophysiological state is isolated and claimed to be type-identical to the state of desiring. (shrink)

Kenny, A. Descartes on the will.--McRae, R. Innate ideas.--McRae, R. Descartes' definition of thought.--Gombay, A. Cogito ergo sum: inference or argument?--Ashworth, E. J. Descartes' theory of clear and distinct ideas.--Alexander, R. E. The problem of metaphysical doubt and its removal.--Tweyman, S. The reliability of reason.--Percival, W. K. On the non-existence of Cartesian linguistics.

The importance of communities in strengthening the ethics of international collaborative research is increasingly highlighted, but there has been much debate about the meaning of the term ‘community’ and its specific normative contribution. We argue that ‘community’ is a contingent concept that plays an important normative role in research through the existence of morally significant interplay between notions of community and individuality. We draw on experience of community engagement in rural Kenya to illustrate two aspects of this interplay: (i) that (...) taking individual informed consent seriously involves understanding and addressing the influence of communities in which individuals’ lives are embedded; (ii) that individual participation can generate risks and benefits for communities as part of the wider implications of research. We further argue that the contingent nature of a community means that defining boundaries is generally a normative process itself, with ethical implications. Community engagement supports the enactment of normative roles; building mutual understanding and trust between researchers and community members have been important goals in Kilifi, requiring a broad range of approaches. Ethical dilemmas are continuously generated as part of these engagement activities, including the risks of perverse outcomes related to existing social relations in communities and conditions of ‘half knowing’ intrinsic to processes of developing new understandings. (shrink)

This paper explores some key discrepancies between two sets of normative requirements applicable to the research use of personal data and human biological materials: the data protection regime which follows the application of the European Union General Data Protection Regulation, and the Declaration of Helsinki, CIOMS guidelines and other research ethics regulations. One source of this controversy is that the GDPR requires consent to process personal data to be clear, concise, specific and granular, freely given and revocable and therefore has (...) challenged the concept of ‘broad consent’, which has been widely applied in the context of biobanking. Another source of controversy is the interplay between regulations of research ethics and protection of personal data related to the secondary use of personal data and biological materials. In this case, the GDPR ‘research condition’ provides an alternative to re-consent for the use of previously collected personal data and biological materials. Although the mentioned controversies have been raised in the legal literature, they have not been explicitly addressed from the research ethics perspective. Should consent be regarded as a priority legal basis for personal data processing in health data research? Can broad consent still be a suitable legal ground for biobanking? What should be the role of research ethics provisions that differ from the GDPR standards, and what should be the role and function of research ethics committees in the changing environment of health data research? These are the ongoing controversies to be explored in the paper. (shrink)

The present study examined the neural substrate of two classes of quantifiers: numerical quantifiers like ” at least three” which require magnitude processing, and logical quantifiers like ” some” which can be understood using a simple form of perceptual logic. We assessed these distinct classes of quantifiers with converging observations from two sources: functional imaging data from healthy adults, and behavioral and structural data from patients with corticobasal degeneration who have acalculia. Our findings are consistent with the claim that numerical (...) quantifier comprehension depends on a lateral parietal-dorsolateral prefrontal network, but logical quantifier comprehension depends instead on a rostral medial prefrontal-posterior cingulate network. These observations emphasize the important contribution of abstract number knowledge to the meaning of numerical quantifiers in semantic memory and the potential role of a logic-based evaluation in the service of non-numerical quantifiers. (shrink)

This paper explores how an institution of higher education in partnership with a local parent-led organization can support authentic and organic Latinx family engagement and advocacy for dual language bilingual, bicultural, biliterate education (DLB3E). We reflect upon how engaging with Spanish-speaking parents helped us reimagine, reinvigorate, and transform local schools and universities by means of new understandings and practices of linguistic and cultural wealth, community assets, and family empowerment. We argue that this form of collaboration can lead to innovative and (...) positive changes in p-16 education. To demonstrate, we share our developing framework for organizing annual parent conferences hosted by the University of Texas Rio Grande Valley’s Center for Bilingual Studies in partnership with RGV PUEDE (Rio Grande Valley Parents United for Excellent Dual Education/Padres Unidos para una Educación Dual de Excelencia). Our framework shows how to build and strengthen grassroots parent and community advocacy for DLB3E from pre-kindergarten through university by strengthening partnerships between parents, public schools, university faculty, and nonprofit organizations to organize conferences and other types of public conversations in Spanish. (shrink)

OBJECTIVES: To investigate the need for hospital clinical ethics committees by studying the frequency with which ethical dilemmas arose, the perceived adequacy of the process of their resolution, and the teaching and training of staff in medical ethics. DESIGN: Interviews with individuals and three multidisciplinary teams; questionnaire to randomly selected individuals. SETTING: Two major London children's hospitals. RESULTS: Ethical dilemmas arose frequently but were resolved in a relatively unstructured fashion. Ethical concerns included: the validity of consent for investigations and treatment; (...) lack of children's involvement in consent; initiation of heroic or futile treatments; resource allocation. Staff expressed the need for a forum which would provide consultation on ethical issues, develop guidelines for good ethical practice, undertake teaching and training, and provide ethical reflection outside the acute clinical setting. CONCLUSION: Multidisciplinary, accountable and audited clinical ethics committees with predominantly advisory, practice development and educational roles could provide a valuable contribution to UK clinical practice and perhaps in other countries that have not developed hospital clinical ethics committees. (shrink)

This paper discusses the relation between cognitive and implementational levels of analysis. Chalmers (1990, 1993) argues that a connectionist implementation of a classical cognitive architecture possesses a compositional semantics, and therefore undercuts Fodor and Pylyshyn's (1988) argument that connectionist networks cannot possess a compositional semantics. I argue that Chalmers argument misconstrues the relation between cognitive and implementational levels of analysis. This paper clarifies the distinction, and shows that while Fodor and Pylyshyn's argument survives Chalmers' critique, it cannot be used to (...) establish the irrelevance of neurophysiological implementation to cognitive modeling; some aspects of Chater and Oaksford's (1990) response to Fodor and Pylyshyn, though not all, are therefore cogent. (shrink)

We review the history of the road to a manifestly covariant perturbative calculus within quantum electrodynamics from the early semi-classical results of the mid-twenties to the complete formalism of Stueckelberg in 1934. We choose as our case study the calculation of the cross-section of the Compton effect. We analyse Stueckelberg's paper extensively. This is our first contribution to a study of his fundamental contributions to the theoretical physics of the twentieth century.

On the traditional view, Butler maintains that forgiveness involves a kind of “conversion experience” in which we must forswear or let go of our resentment against wrongdoers. Against this reading, I argue that Butler never demands that we forswear resentment but only that we be resentful in the right kind of way. That is, he insists that we should be virtuously resentful, avoiding both too much resentment exhibited by the vices of malice and revenge and too little resentment (...) where we merely condone the wrongdoer and leave ourselves open to future injury. I argue that this Butlerian approach offers us a more attractive account of forgiveness as a “virtue” than many recent discussions. In the final section, I address Butler’s challenging thesis that forgiveness is an unconditional moral duty. I argue against those who claim that forgiveness is supererogatory (Kolnai/Calhoun) or else merely morally conditional and even morally blameworthy in some cases (Murphy/Hampton/Novitz/Richards). By contrast, I defend a context-sensitive account of forgiveness which recognizes that it takes place on many different levels. I conclude by taking up the difficult issue of whether anybody can be ultimately “unforgivable”, offering some Butlerian and Strawsonian reflections that might help mitigate our judgments about such matters. (shrink)

In Cratylus 385 b-c Plato argues that if statements () can be true or false, names (),2 as parts () of statements, are also capable of being true or false. From Aristotle onwards this view has often been challenged,3 and R. Robinson put the case against it trenchantly when he wrote:4This argument is bad; for names have no truth-value, and the reason given for saying that they do is a fallacy of division. No one in the dialogue points out that (...) it is bad. … Nevertheless it is fairly probable that Plato saw or at least felt that it is a bad argument, quite different in quality from those he later produces against the nature-theory. (shrink)

Case-based, multidisciplinary seminars provided a vehicle for clinicians, philosophers and students to debate current problems in medical ethics in a manner which ensured maximum learning and interest for all participants. Prior training in philosophical medical ethics was an essential prerequisite, giving students the knowledge and skills to take part in the discussions at an appropriate level of sophistication.

The current rise in malpractice litigation has led to concern in the research community as to the prospect of litigation against researchers. Clearly as the responsibility for the day-to-day conduct of the research falls upon the researchers they will be potentially liable should there be negligence in the conduct of the research project itself. But to what extent can the research ethics committee and its members be held liable should harm result to the research subject? How far does the prospect (...) of the threat of litigation equate with the reality of the prospect of liability? Although the NHS research governance framework suggests that primary responsibility for the conduct of the trial is with the researcher this does not mean that REC members will be immune from actions in tort where research subjects suffer harm in the conduct of a research project approved by their NHS REC. This paper focuses upon the prospect for liability in the law of tort of NHS RECs and their members. While in practice the vast majority of such claims are unlikely to be successful members of RECs may incur resultant legal costs as a consequence of involvement in proposed litigation. It is submitted that the scope of indemnity provision provided to RECs and their members should be precisely determined, otherwise there is a real prospect that the risk of malpractice litigation may deter individuals from serving on such committees. (shrink)

The paper discusses the philosophical and historical doctrine of the Russian philosopher and historian George Petrovich Fedotov. The author focuses on the analysis of imperial issues in the works of G.P. Fedotov, especially of his views on the cultural history of the Russian empire and the essence of imperial project in Russia. Fedotov reconsiders the historical experience and revolutionary catastrophe of Russia and searches for the foundations of the social and cultural processes determining the events of Russian history. Fedotov’s works (...) offer a variety of interpretations of the political and cultural phenomenon of empire. This reflects his evolution as a philosopher of history: the focus of his vision shifts from the Medieval Rus to the Empire of Peter the Great, then to the collapsed empire of Nicholas II and finally to the USSR. Fedotov’s concept of Empire evolves into a timeless cultural-philosophical phenomenon but originates from the historical description of the centralization of power in the feudal monarchy of Ivan the Terrible. The evolution of the philosophical and historical views of Fedotov is influenced by the changes of his attitude to the historical conception of Klyuchevsky. In the 1940s Fedotov considers the empire as a universal idea. The concept of empire proposed by Fedotov gives an understanding of the Russian historical development, especially the causes of the decline and fall of the Russian Empire. Fedotov associates the cause of the salvation of Russia with the study of ancient Russian culture, in which he founds a moral and political ideal of the “Republic of Saint Sophia.” The paper shows heuristic potential of Fedotov’s cultural and philosophical ideas on the vocation of spiritual elite and the creative role of personality in the process of nation-building. (shrink)

Interest in science and math plays an important role in encouraging STEM motivation and career aspirations. This interest decreases for girls between late childhood and adolescence. Relatedly, positive mentoring experiences with female teachers can protect girls against losing interest. The present study examines whether visitors to informal science learning sites differ in their expressed science and math interest, as well as their science and math stereotypes following an interaction with either a male or female educator. Participants were visitors to one (...) of four ISLS in the United States and United Kingdom. Following an interaction with a male or female educator, they reported their math and science interest and responded to math and science gender stereotype measures. Female participants reported greater interest in math following an interaction with a female educator, compared to when they interacted with a male educator. In turn, female participants who interacted with a female educator were less likely to report male-biased math gender stereotypes. Self-reported science interest did not differ as a function of educator gender. Together these findings suggest that, when aiming to encourage STEM interest and challenge gender stereotypes in informal settings, we must consider the importance of the gender of educators and learners. (shrink)

The Human Tissue Act 2004 presents a radical change to the legal regulation of the use of human material in England and Wales. The Act presents a broad regulatory framework but much in the practical operation of the legislation will depend upon regulations to be enacted and a new Code of Practice. This article examines 'appropriate consent' for the use of human tissue for research purposes in the context of the living competent adult. It examines the provision of information as (...) part of the consent process for the use of human materials for research purposes, the question of when consent can be withdrawn, and the controversial exception enabling the use without consent of anonymized material for research purposes where the research has been ethically approved. The paper concludes by highlighting some of the problems which may remain after the legislation comes into force. (shrink)

In the philosophy of mathematical practice, the aim is to understand the various aspects of this practice. Even though definitions are a central element of mathematical practice, the study of this aspect of mathematical practice is still in its infancy. In particular, there is little empirical evidence to substantiate claims about definitions in practice. In this article, we address this gap by reporting on an empirical investigation on how mathematicians create definitions and which roles and properties they attribute to them. (...) On the basis of interviews with thirteen research mathematicians, we provide a broad range of relevant aspects of definitions. In particular, we address various roles of definitions and show that definitions are not just a product of mathematical factors, but also of social and contingent factors. Furthermore, we provide concrete examples of how mathematicians interact and think about definition. This broad empirical basis with a variety of examples provides an optimal starting point for future investigations into definitions in mathematical practice. (shrink)

Definitions are traditionally seen as abbreviations, as tools for notational convenience that do not increase inferential power. From a Philosophy of Mathematical Practice point of view, however, there is much more to definitions. For example, definitions can play a role in problem solving, definitions can contribute to understanding, sometimes equivalent definitions are appreciated differently, and so on. This chapter reviews the literature on definitions and (to a certain extent) concepts in mathematical practice. It is structured according to four themes through (...) which definitions (and concepts) in mathematical practice have been studied. These themes concern (1) the nature of definitions, (2) whether and how concepts evolve, (3) definitions and concepts from a communal perspective, and (4) different values relating to definitions and concepts. (shrink)